Juncheng Chen Selected Research

4-hydroxyquinazoline

12/2022

Discovery of 4-Hydroxyquinazoline Derivatives as Small Molecular BET/PARP1 Inhibitors That Induce Defective Homologous Recombination and Lead to Synthetic Lethality for Triple-Negative Breast Cancer Therapy.

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Juncheng Chen Research Topics

Disease

6	Neoplasms (Cancer) 01/2022 - 01/2016
3	Triple Negative Breast Neoplasms 12/2022 - 01/2021
2	Insulin Resistance 02/2022 - 12/2018
1	Breast Neoplasms (Breast Cancer) 12/2022
1	Body Weight (Weight, Body) 05/2022
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022
1	Infections 01/2022
1	Melanoma (Melanoma, Malignant) 01/2022
1	Virus Diseases (Viral Diseases) 01/2022
1	Amyloidosis 04/2021
1	Obesity 12/2018

Drug/Important Bio-Agent (IBA)

3	Proteins (Proteins, Gene)FDA Link 12/2022 - 12/2021
1	4-hydroxyquinazolineIBA 12/2022
1	emu OilIBA 05/2022
1	GlucosidasesIBA 02/2022
1	ErbB Receptors (EGF Receptor)IBA 01/2022
1	Antiviral Agents (Antivirals)IBA 01/2022
1	Carrier Proteins (Binding Protein)IBA 01/2022
1	Histones (Histone)IBA 01/2022
1	Indicators and Reagents (Reagents)IBA 01/2022
1	Interferon Type IIBA 01/2022
1	Poly I-CIBA 01/2022
1	Double-Stranded RNA (RNA, Double Stranded)IBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 01/2022
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2022
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2022
1	osimertinibIBA 01/2022
1	Casein Kinase II (Casein Kinase 2)IBA 12/2021
1	Prealbumin (Transthyretin)IBA 04/2021
1	diphosphoric acid (pyrophosphoric acid)IBA 04/2021
1	Pharmaceutical PreparationsIBA 01/2021
1	Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA 01/2021
1	MicroRNAs (MicroRNA)IBA 01/2021
1	oxidized low density lipoproteinIBA 12/2018
1	Glucose (Dextrose)FDA LinkGeneric 12/2018
1	Polysaccharides (Glycans)IBA 12/2018
1	Triglycerides (Triacylglycerol)IBA 12/2018
1	LDL CholesterolIBA 12/2018
1	CholesterolIBA 12/2018
1	Harmine (Telepathine)IBA 01/2016

Therapy/Procedure

4	Therapeutics 12/2022 - 12/2021